KN-297 Oppen

【Laboratory animal’s ID marker】
Over 13,000 Units Shipped Worldwide — Used in 10 Countries Around the Globe 

・Capable of marking the tail and skin of not only albino mice but also colored mice such as C57BL/6.

・Animal-safe inks are used.

・Available in five colors.

・With its fine tip, eve small numbers and characters can be written clearly without smudging, expanding the range of identification options. NEW！

If you wish to identifiy by hair, Animal markeris recommended.

■ Animal-safe inks are used. Acute oral toxicity testing has been conducted.
　Final report of the acute oral toxicity test (Summary)

■ Beyond identification of mice and rats,
Oppen can also be used for rabbits, marmosets, and other animals.
It is suitable for marking ears, tails, and skin, including during surgical procedures.

１）Examples of marking using Oppen (Illustration: ear & tail)

２）Examples of marking using Oppen (Photo: rabbit ear)
*Courtesy of National Center for Biomodels (Taiwan)
*Animal: Narl:NZW (Female, approximately 4–5 months old), Housing: Single housing (for experimental purposes).

■ Customer Feedback & Case Studies on Oppen
　Case1：Albino Mouse×Pink・Light Blue
 Case2：B6×Pink
 Case3：B6（2 weeks old）×All colors
 Case4：B6（4 months old）×All colors
 Case5：B6（6 months old）×All colors

■ Customer Feedback & Case Studies on Oppen for Numbers
　Case6：Albino×Light Blue
 Case7：Albino×Pink
 Case8：B6×Light Blue
 Case9：B6×Pink

Introduced on norecopa a database site for 3Rs(laboratory animal welfare) products headquartered in Norway.

* About Oppen in Japanese

■ Information Related to Oppen (Reference Literature Included)
①Rhodamine 6G in Stationery (e.g., Markers)
Fluorescent-colored stationery products (such as markers) may commonly containRhodamine 6G as a coloring agent.
For Oppen products, the presence of Rhodamine 6G has been confirmed in Oppen Pink.
When using pens or markers, please select the appropriate color according to your research or experimental objectives.
＊Rhodamine 6G is not contained in Oppen Black, Light Blue, Violet, or Green.
＊Please note that the potential impact on experiments involving fluorescence has not been fully evaluated. Use with appropriate consideration.

[Reference]
Foshe S, Shi S, Bell BA, Lee S, Shankar A, Dine K, Song Y, Vithayathil J, Ross AG, Dunaief JL.
A remarkable tale: increased retinal fluorescence following application of permanent marker ink to mouse tails. Invest Ophthalmol Vis Sci. 2026;67(3):40. doi:10.1167/iovs.67.3.40

②Comparison Between Markers and Other Identification Methods
 [Reference]
１）Burn CC, Mazlan NHB, Chancellor N, Wells DJ. The Pen Is Milder Than the Blade: Identification Marking Mice Using Ink on the Tail Appears More Humane Than Ear-Punching Even with Local Anaesthetic. Animals (Basel). 2021;11(6):1664. Published 2021 Jun 3. doi:10.3390/ani11061664

■ Request for Information Sharing
If you have relevant knowledge, data, or literature related to this topic, we would greatly appreciate your contribution. With the aim of improving experimental reproducibility and promoting animal welfare, we may review and consider sharing such information on this page.
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